NFC WestPower #1013-6 SU11-8 ATS11-8 O/U
San Francisco 49ers went 13-6 straight up, 11-8 against the spread (58% covers, average cover margin +1.3 points), 11-8 on over/unders in 2025, including 8-3 ATS as a favorite and 3-5 ATS as an underdog.
Last 5 (result · ATS · O/U):WWO·WLO·LLU·WWU·LLO
Season at a glance13-6 SU · 11-8 ATS
Straight up
13-6
68% wins
Power rating
+1.9 #10
SOS +1.0
Against the spread
11-8
58% covers
Avg cover margin
+1.3
points vs the line
Over / Under
11-8
58% overs
Points for / against
24.5 / 22.7
per game
San Francisco 49ers 2025 schedule, lines & results
19 played · 0 to go
| Week | Date | Opponent | Line | Total | Result | ATS | O/U | Game details |
|---|---|---|---|---|---|---|---|---|
| 1 | Sep 7 |  @ Seattle Seahawks |
-1.5 | 44.5 | W 17-13 | W +2.5 | U | |
| 2 | Sep 14 |  @ New Orleans Saints non-div |
-2.5 | 40.5 | W 26-21 | W +2.5 | O Q4 | |
| 3 | Sep 21 |  Arizona Cardinals |
-1.5 | 43.5 | W 16-15 | L -0.5 | U | |
| 4 | Sep 28 |  Jacksonville Jaguars non-div |
-3.5 | 46.5 | L 21-26 | L -8.5 | O Q4 | |
| 5 | Oct 2 |  @ Los Angeles Rams |
+8.5 | 43.5 | W 26-23 | W +11.5 | O Q4 | |
| 6 | Oct 12 |  @ Tampa Bay Buccaneers non-div |
+3.5 | 46.5 | L 19-30 | L -7.5 | O Q4 | |
| 7 | Oct 19 |  Atlanta Falcons non-div |
+1.5 | 46.5 | W 20-10 | W +11.5 | U | |
| 8 | Oct 26 |  @ Houston Texans non-div |
+3.5 | 41.5 | L 15-26 | L -7.5 | U | |
| 9 | Nov 2 |  @ New York Giants non-div |
-2.5 | 47.5 | W 34-24 | W +7.5 | O Q4 | |
| 10 | Nov 9 | Los Angeles Rams |
+6.5 | 49.5 | L 26-42 | L -9.5 | O Q4 | |
| 11 | Nov 16 | @ Arizona Cardinals |
-3.5 | 48.5 | W 41-22 | W +15.5 | O Q4 | |
| 12 | Nov 24 |  Carolina Panthers non-div |
-7 | 48.5 | W 20-9 | W +4 | U | |
| 13 | Nov 30 |  @ Cleveland Browns non-div |
-5.5 | 35.5 | W 26-8 | W +12.5 | U | |
| 15 | Dec 14 |  Tennessee Titans non-div |
-12.5 | 44.5 | W 37-24 | W +0.5 | O Q4 | |
| 16 | Dec 22 |  @ Indianapolis Colts non-div |
-4.5 | 46.5 | W 48-27 | W +16.5 | O Q3 | |
| 17 | Dec 28 |  Chicago Bears non-div |
-4.5 | 51.5 | W 42-38 | L -0.5 | O Q3 | |
| 18 | Jan 3 | Seattle Seahawks |
+2.5 | 48.5 | L 3-13 | L -7.5 | U | |
| Post | Jan 11 |  @ Philadelphia Eagles non-div |
+5.5 | 44.5 | W 23-19 | W +9.5 | U | |
| Post | Jan 17 | @ Seattle Seahawks |
+7 | 44.5 | L 6-41 | L -28 | O Q4 |
San Francisco 49ers 2025 ATS and over/under splits
Home, away, favorite, underdog and conference
| Situation | SU | ATS | Cover % | Avg margin | O/U | PF | PA |
|---|---|---|---|---|---|---|---|
| All games | 13-6 | 11-8 | 58% | +1.3 | 11-8 | 24.5 | 22.7 |
| Home | 5-3 | 3-5 | 38% | -1.3 | 4-4 | 23.1 | 22.1 |
| Away | 8-3 | 8-3 | 73% | +3.2 | 7-4 | 25.5 | 23.1 |
| As favorite | 10-1 | 8-3 | 73% | +4.7 | 7-4 | 29.8 | 20.6 |
| As underdog | 3-5 | 3-5 | 38% | -3.4 | 4-4 | 17.3 | 25.5 |
| Division games | 4-3 | 3-4 | 43% | -2.3 | 4-3 | 19.3 | 24.1 |
| Non-division games | 9-3 | 8-4 | 67% | +3.4 | 7-5 | 27.6 | 21.8 |
How San Francisco 49ers’s 2025 games played out
Quarter the total was passed, when covers were settled, halftime leads
11 of 19 games went over · quarter the total was passed
Q3 11% 2
Q4 47% 9
Stayed under 42% 8
11 covers: 2 settled only in the 4th quarter or overtime
Led at halftime 11: won 11, covered 9
Trailed at halftime 8: won 2, covered 2
Research San Francisco 49ers games by quarter ›